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Kojic Acid Powder

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    Negotiable

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    The date of payment from buyers deliver within days

  • seat:

    Beijing

  • Validity to:

    Long-term effective

  • Last update:

    2021-06-24 06:40

  • Browse the number:

    341

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Greenway Biotech Co., Ltd
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Contact:

szgelinwei(Mr.)  

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Telephone:

Phone:

Area:

Beijing

Address:

No.3, Xupai Road, Huqiu District, Suzhou City, Jiangsu Province, China

Website:

http://www.greenwaybiotek.com/ http://szgelinwei.kawayin.com/

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Product Details

Kojic Acid



Solubility


In Vitro

DMSO:≥50 mg/mL(703.68 mM)

H2O:33.33 mg/mL(351.84 mM;Need ultrasonic)

Preparing 

Stock Solutions

Concentration/Solvent/Mass

1 mg

5 mg

10 mg

1 mM

7.0368ml

35.1840ml

70.3680ml

5 mM

1.4074ml

7.0368ml

14.0736ml

10 mM

0.7037ml

3.5184ml

7.0368ml

Please refer to the solubility information to select the appropriate solvent.

1.Add each solvent one by one: 10% DMSO >>40% PEG300 >>5% Tween-80>>45% saline

Solubility: ≥2.5mg/ml(9.18mM); Clear Solution

2.Add each solvent one by one: 10% DMSO >>90% (20%SBE-β-CD in saline)

Solubility: ≥2.5mg/ml(9.18mM); Clear Solution

3.Add each solvent one by one: 10% DMSO >>90% corn oil

Solubility: ≥2.5mg/ml(9.18mM); Clear Solution

Items

Specifications

Results

Appearance Property

Almost White or Light Yellow Crystal or Crystal line Powder

Almost White Crystal

Assay,%

99.0 Min

99.96

Melting Point,℃

152-155

153.6-153.7

Loss on Drying,%

0. 5 Max

0.2

Residue on Ignition,%

0.10 Max

0.05

Chlorides(as Cl),%

0.005 Max

0.005

Heavy Metals(as Pb),%

0.001 Max

0.001

Iron(as Fe),%

0.001 Max

0.001


Function of kojic acid


Kojic acid (cas 501-30-4) is used in the field of cosmetics. In human skin, tyrosine undergoes complex oxidation and polymerization with oxygen free radicals under the catalysis of tyrosinase, and finally synthesizes melanin. Kojic acid can inhibit the synthesis of tyrosinase, so it can strongly inhibit the formation of melanin in the skin. It is safe and non-toxic, and will not produce sequelae of leukoplakia. Therefore, Kojic acid has been formulated into lotions, facial masks, lotions, and skin creams. It can effectively treat freckles, age spots, pigmentation, acne and other high-end whitening cosmetics. Kojic acid at a concentration of 20ug/ml can inhibit 70-80% of the activity of a variety of tyrosinase (or polyphenol oxidase PPO), and the general addition amount in cosmetics is 0.5-2.0%.


Precautions for kojic acid


1. Kojic acid powder is unstable to light, heat and metal ions. Do not add it at high temperature when formulating, and control the content of iron and other metal ions in the system.

2. It is best to add appropriate complexing agents such as EDTA and antioxidants such as sodium sulfite to the system;

3. Kojic acid powder Suggested dosage  : 0.5~2.0%.


http://www.greenwaybiotek.com/